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Analysis of Cerebrospinal Fluid Soluble TREM2 and Polymorphisms in Sporadic Parkinson's Disease in a Chinese Population.

Guoyou PengJiewen QiuHanqun LiuMiaomiao ZhouShuxuan HuangWenyuan GuoYuwan LinXiang ChenZhe LiGuihua LiWenlong ZhangYunlong ZhangXingjian LiZhuohua WuLei WeiXinling YangXiaoqin ZhuMingshu MoPing-Yi Xu
Published in: Journal of molecular neuroscience : MN (2019)
Although it may not indicate that exon 2 polymorphisms of TREM2 play a role in the pathogenesis of PD in the Chinese population, our findings described above highlight the relevance of CSF sTREM2 as a promising biomarker and are extremely possible to the therapeutic target for PD in the future.
Keyphrases
  • cerebrospinal fluid
  • late onset
  • current status