UCHL1 promotes the proliferation of porcine granulosa cells by stabilizing CCNB1.

Shengjie ShiHuan YuanLutong ZhangLei GaoLili ZhaoXiangfang ZengShiyan QiaoGuiyan ChuChuanjiang Cai

Published in: Journal of animal science and biotechnology (2024)

UCHL1 promoted the proliferation of porcine GCs by stabilizing CCNB1, and isovitexin enhanced the enzyme activity of UCHL1. These findings reveal the role of UCHL1 and the potential of isovitexin in regulating proliferation and provide insights into identifying molecular markers and nutrients that affect follicle development.

Keyphrases

signaling pathway
induced apoptosis
heavy metals
risk assessment
gene expression
metabolic syndrome
human health
insulin resistance