Palladium-Catalyzed Regiodivergent Substitution of Propargylic Carbonates.
Theresa M LocascioJon A TungePublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2016)
The palladium(0)-catalyzed, ligand-controlled, regioselective addition of diaryl acetonitrile pronucleophiles to propargylic carbonates is reported. Selective formation of either terminal 1,3-dienyl or propargylated products is proposed to arise from a change in reaction mechanism controlled by the denticity of the coordinating ligand.
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