Decreased platelet activation predicts hepatic decompensation and mortality in patients with cirrhosis.
Benedikt Silvester HoferKsenia BrusilovskayaBenedikt SimbrunnerLorenz BalcarBeate EichelbergerSilvia LeeLukas HartlPhilipp SchwablMattias MandorferSimon PanzerThomas ReibergerThomas GremmelPublished in: Hepatology (Baltimore, Md.) (2023)
Preserved PAR-1- and PAR-4-inducible platelet activation was linked to a lower risk of decompensation and death. In contrast, higher epinephrine-inducible platelet activation was a risk factor for thromboembolism and PVT.
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