Alterations of the iNKT cell compartment in brain-injured patients.

Allan PatinecJézabel RocherMickael Vourc'hAntoine RoquillyKarim AsehnouneJacques Le Pendu

Published in: Critical care (London, England) (2019)

We observed severe alterations of the iNKT cell compartment, including the presence of inhibitory serum factors. We demonstrate for the first time that the decreased capacity to present antigens is not a generalized phenomenon because whereas the expression of HLA-DR molecules is decreased, the capacity for presenting glycolipids through CD1d expression is higher in patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
single cell
peritoneal dialysis
multiple sclerosis
stem cells
patient reported outcomes
mesenchymal stem cells
brain injury
patient reported