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ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness.

Yin LiuPuspa R PandeySambad SharmaFei XingKerui WuAmar ChittiboyinaShih-Ying WuAbhishek TyagiKounosuke Watabe
Published in: Breast cancer research and treatment (2019)
Our results indicate that ID2 is a key driver of DCIS formation and therefore is considered to be a potential target for prevention of DCIS, while INHBA and GJB2 play vital roles in progression of DCIS to IDC and they may serve as potential prognosis markers.
Keyphrases
  • early stage
  • stem cells
  • papillary thyroid
  • hearing loss
  • human health
  • squamous cell carcinoma
  • squamous cell
  • radiation therapy
  • signaling pathway
  • sentinel lymph node
  • lymph node
  • climate change
  • neoadjuvant chemotherapy