ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness.

Yin LiuPuspa R PandeySambad SharmaFei XingKerui WuAmar ChittiboyinaShih-Ying WuAbhishek TyagiKounosuke Watabe

Published in: Breast cancer research and treatment (2019)

Our results indicate that ID2 is a key driver of DCIS formation and therefore is considered to be a potential target for prevention of DCIS, while INHBA and GJB2 play vital roles in progression of DCIS to IDC and they may serve as potential prognosis markers.

Keyphrases

early stage
stem cells
papillary thyroid
hearing loss
human health
squamous cell carcinoma
squamous cell
radiation therapy
signaling pathway
sentinel lymph node
lymph node
climate change
neoadjuvant chemotherapy