ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness.
Yin LiuPuspa R PandeySambad SharmaFei XingKerui WuAmar ChittiboyinaShih-Ying WuAbhishek TyagiKounosuke WatabePublished in: Breast cancer research and treatment (2019)
Our results indicate that ID2 is a key driver of DCIS formation and therefore is considered to be a potential target for prevention of DCIS, while INHBA and GJB2 play vital roles in progression of DCIS to IDC and they may serve as potential prognosis markers.