Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation.

Li LiXulin XuKeyu LvGuijuan ZhengHao WangShuai ChenLang HuangYi LiuYadong ZhangZhaoming TangLili ZhangJinyu WangJianlin QiaoHongliang LiXuanbin WangGuangmin YaoChao Fang

Published in: British journal of pharmacology (2022)

Asebogenin exhibits potent antithrombotic effects by targeting Syk and is a potential lead compound for the development of efficient and safe antithrombotic agents.

Keyphrases

tyrosine kinase
atrial fibrillation
signaling pathway
protein kinase
risk assessment