Sensitive universal detection of blood parasites by selective pathogen-DNA enrichment and deep amplicon sequencing.
Briana R FlahertyJoel Leonard Nicholas BarrattMeredith LaneEldin TalundzicRichard S BradburyPublished in: Microbiome (2021)
The assay detects and differentiates the major malaria parasites of humans, along with several other clinically important blood parasites. This represents an important step towards a TADS-based universal parasite diagnostic (UPDx) test with a sufficient LOD for routine applications. Video Abstract.