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Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults.

Sarah SpencerJessie R ChungEdward A BelongiaMaria E SundaramJennifer MeeceLaura A ColemanRichard K ZimmermanMary Patricia NowalkKrissy Moehling GeffelTed M RossChalise E CarterDavid K ShayMin LevineJustine LiepkalnsJin Hyang KimSuryaprakash SambharaMark G ThompsonBrendan Flannery
Published in: Influenza and other respiratory viruses (2021)
Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine in adults aged 50-80 with and without type 2 diabetes mellitus. Serologic response to influenza vaccination was similar in both groups: greater fold-increases in antibody titer occurred among participants with lower pre-vaccination antibody titers. Waning of antibody titers was not influenced by diabetes status.
Keyphrases
  • glycemic control
  • type diabetes
  • cardiovascular disease
  • physical activity
  • respiratory syndrome coronavirus
  • risk factors
  • adipose tissue
  • sars cov
  • cardiovascular risk factors