Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults.
Sarah SpencerJessie R ChungEdward A BelongiaMaria E SundaramJennifer MeeceLaura A ColemanRichard K ZimmermanMary Patricia NowalkKrissy Moehling GeffelTed M RossChalise E CarterDavid K ShayMin LevineJustine LiepkalnsJin Hyang KimSuryaprakash SambharaMark G ThompsonBrendan FlanneryPublished in: Influenza and other respiratory viruses (2021)
Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine in adults aged 50-80 with and without type 2 diabetes mellitus. Serologic response to influenza vaccination was similar in both groups: greater fold-increases in antibody titer occurred among participants with lower pre-vaccination antibody titers. Waning of antibody titers was not influenced by diabetes status.