Individualized risk components guiding antipsychotic delivery in patients with a clinical high risk of psychosis: application of a risk calculator.
Tian Hong ZhangLiHua XuHuiJun LiHuiRu CuiYingYing TangYanYan WeiXiaoChen TangYeGang HuLi HuiChunBo LiMargaret A NiznikiewiczMartha E ShentonMatcheri S KeshavanWilliam S StoneJiJun WangPublished in: Psychological medicine (2021)
Through applying a personal risk assessment, the administration of antipsychotics should be limited to CHR individuals with predominantly positive symptoms and related function decline. A strict antipsychotic prescription strategy should be introduced to reduce inappropriate use.