Dynamic pattern of postprandial bile acids in paediatric non-alcoholic fatty liver disease.

Jiating HuangHu LinA-Na LiuWei WuAnna Alisi Stephen CaldwellCuifang XuWenqin XiangJie ShaoGuanping DongMing-Hua ZhengJunfen FuYan Ni

Published in: Liver international : official journal of the International Association for the Study of the Liver (2024)

This study provides novel insights into the dynamics of BAs during OGTT in paediatric NAFLD. The observed variations in CDCA and HCA species were associated with liver dysfunction, dyslipidaemia and dysglycaemia, highlighting their potential roles as promising diagnostic and therapeutic targets in NAFLD.

Keyphrases

intensive care unit
emergency department
blood glucose
type diabetes
insulin resistance
liver fibrosis
skeletal muscle
weight loss