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Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis.

Rebecca A SymonsFabio ColellaFraser L CollinsAlexandra J RafipayKarolina KaniaJessica J McClureNathan WhiteIain CunninghamSadaf AshrafElizabeth HayKevin S MackenzieKenneth A HowardAnna H K RiemenAntonio ManzoSusan M ClarkAnke J RoelofsCosimo De Bari
Published in: Annals of the rheumatic diseases (2021)
Our findings uncover the IL-6-Yap-Snail signalling axis in pathogenic SF in inflammatory arthritis.
Keyphrases
  • epithelial mesenchymal transition
  • rheumatoid arthritis
  • oxidative stress
  • cancer therapy
  • extracellular matrix