GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data.

Shoaib AjaibDisha LodhaSteven PollockGemma HemmingsMartina A FinettiArief GusnantoAruna ChakrabartyAzzam IsmailErica WilsonFrederick S VarnBethany HunterAndrew FilbyAsa A BrockmanDavid McDonaldRoel G W VerhaakRebecca A IhrieLucy F Stead

Published in: Neuro-oncology (2023)

GBMdeconvoluteR accurately quantifies immune and neoplastic cell proportions in IDHwt GBM bulk RNA sequencing data and is accessible here: https : // gbmdeconvoluter.leeds.ac.uk.

Keyphrases

single cell
electronic health record
big data
bone marrow