Family Building Perspectives of Assigned Female at Birth Transgender and Gender Diverse Adolescents Seeking Testosterone Gender-Affirming Hormone Therapy.

<b><i>Purpose:</i></b> The purpose of this study was to assess the future family building desires of assigned female at birth (AFAB) transgender and gender diverse (TGD) adolescents initiating hormone therapy, and to characterize the individuals interested in adoption. <b><i>Methods:</i></b> This was a retrospective chart review of AFAB TGD adolescents ages 15-17 years old initiating testosterone gender-affirming hormone therapy between 2010 and 2019, analyzing interest in adoption, demographics, and gender-affirming care. <b><i>Results:</i></b> Of 195 AFAB TGD adolescents asked about family planning goals, 58% (<i>n</i> = 113) indicated desire for adoption in their future, and 13.3% (<i>n</i> = 26) had no desire for children. There was no difference between those who did and did not want to adopt in terms of age at time of first visit (<i>p</i> = 0.22), or race distribution (<i>p</i> = 0.45); however, straight-identified patients were more likely to desire adoption (<i>p</i> = 0.02) than people with other sexual orientations. Fifty-nine percent (<i>n</i> = 110) of those who did not have a history of adoption and/or experience with the child welfare system desired adoption, compared with 22% (<i>n</i> = 2) of those with a history (odds ratio, 5.14; 95% confidence interval, 1.04-25.39; <i>p</i> = 0.05). <b><i>Conclusion:</i></b> Some AFAB TGD adolescents endorse adoption as their desired pathway to parenthood. Clinicians should be sensitive to the complexities of parenthood desires of AFAB TGD patients and have resources to direct patients to more information. Further research is needed to better understand why many AFAB TGD adolescents desire adoption, how this changes with age, and the barriers they face in achieving their goals.