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Integrating genetic and socioeconomic data to predict the progression of nonalcoholic fatty liver disease.

Maria C Rieman-KlinglerJinho JungKaleb TesfaiStephen CaldwellAmy L Non
Published in: American journal of biological anthropology (2024)
Adjusting for education attenuated the effects of genotype and Hispanic ethnicity on liver fibrosis, suggesting that social factors-rather than genes or ethnicity-may be driving disease severity within some populations. Findings reveal the importance of including socioenvironmental controls when considering the role of genetics or ethnicity in complex disease.
Keyphrases
  • liver fibrosis
  • genome wide
  • healthcare
  • mental health
  • electronic health record
  • dna methylation
  • copy number
  • transcription factor
  • artificial intelligence