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Integrative DNA Methylation and Gene Expression Analysis in the Prefrontal Cortex of Mexicans Who Died by Suicide.

Ana L Romero-PimentelDaniel AlmeidaSaid Muñoz-MonteroClaudia RangelRoberto Mendoza-MoralesEli E Gonzalez-SaenzCorina NagyGary ChenZahia AouabedJean-Francois TherouxGustavo TureckiGabriela Martinez-LevyConsuelo Walss-BassNancy Monroy-JaramilloEdith A Fernández-FigueroaAmalia Gómez-CoteroFernando García-DoloresMirna E Morales-MarinHumberto Nicolini
Published in: The international journal of neuropsychopharmacology (2022)
Our study represents the first, to our knowledge, analysis of DNA methylation and gene expression associated with suicide in a Mexican population using postmortem brain, providing novel insights for convergent molecular alterations associated with suicide.
Keyphrases
  • dna methylation
  • gene expression
  • prefrontal cortex
  • genome wide
  • healthcare
  • white matter
  • copy number
  • cerebral ischemia
  • blood brain barrier
  • multiple sclerosis
  • single molecule
  • brain injury
  • subarachnoid hemorrhage