The effect of age on DNA methylation in whole blood among Bangladeshi men and women.
Rick J JansenLin TongMaria ArgosFarzana JasmineMuhammad Rakibuz-ZamanGolam SarwarMd Tariqul IslamHasan ShahriarTariqul IslamMahfuzar RahmanMd YunusMuhammad G KibriyaJohn A BaronHabibul AhsanBrandon L PiercePublished in: BMC genomics (2019)
Our results describe genome-wide features of age-related changes in DNA methylation. The observed associations between age and methylation were generally consistent for both sexes, although the associations tended to be stronger among women. Our population may have unique age-related methylation changes that are not captured in the established methylation-based age prediction model we used, which was developed to be non-tissue-specific.