Intra-tracheal delivery of mesenchymal stem cell-conditioned medium ameliorates pathological changes by inhibiting apoptosis in asthmatic rats.
Rana KeyhanmaneshFatemeh KhodamoradiReza RahbarghaziAfshin RahbarghaziJafar RezaieMahdi AhmadiLeila SalimiAref DelkhoshPublished in: Molecular biology reports (2022)
Our data notified the potency of direct administration of MSC-CM in the alleviation of airway inflammation, presumably by down regulating apoptotic death in pulmonary niche.
Keyphrases
- cell death
- mesenchymal stem cells
- cell cycle arrest
- pulmonary hypertension
- oxidative stress
- endoplasmic reticulum stress
- electronic health record
- signaling pathway
- bone marrow
- big data
- lung function
- mouse model
- anti inflammatory
- cell therapy
- pi k akt
- stem cells
- air pollution
- machine learning
- cell proliferation
- artificial intelligence