Hemodynamic effects of acute hyperoxia: systematic review and meta-analysis.
Bob SmitYvo M SmuldersJohannes C van der WoudenHeleen M Oudemans-van StraatenAngelique M E Spoelstra-de ManPublished in: Critical care (London, England) (2018)
Hyperoxia may considerably decrease cardiac output and increase systemic vascular resistance, but effects differ between patient categories. Heart failure patients were the most sensitive while no hemodynamic effects were seen in septic patients. There is currently no evidence supporting the notion that oxygen supplementation increases oxygen delivery.