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Switching and Discontinuation Patterns Among Patients Stable on Originator Infliximab Who Switched to an Infliximab Biosimilar or Remained on Originator Infliximab.

Timothy FitzgeraldRichard MelsheimerMarie-Hélène LafeuillePatrick LefebvreLaura MorrisonKimberly WoodruffIris LinBruno Emond
Published in: Biologics : targets & therapy (2021)
Patients switching from originator to biosimilar IFX were more likely to switch to another originator biologic (notably back to originator IFX) and discontinue index treatment than those remaining on originator IFX; however, reasons for switching are unknown.
Keyphrases
  • end stage renal disease
  • ulcerative colitis
  • ejection fraction
  • newly diagnosed
  • peritoneal dialysis
  • combination therapy