Subsequent correlated changes in complement component 3 and amyloid beta oligomers in the blood of patients with Alzheimer's disease.

Kyu Hwan ShimDanyeong KimMin Ju KangJung-Min PyunYoung Ho ParkYoung Chul YounKyung Won ParkKyoungho SukHo-Won LeeBárbara Fernandes GomesHenrik ZetterbergSeong Soo Alexander AnSangYun Kimnull null

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Increased plasma C3 in AD are associated with amyloid pathology, possibly reflecting a defense response for Aβ clearance. Further studies on Aβ-binding proteins will enhance understanding of Aβ mechanisms in blood.

Keyphrases

case control
innate immune