HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia.
Flora CimminoMarianna AvitabileVito Alessandro LasorsaAnnalaura MontellaLucia PezoneSueva CantalupoFeliciano VisconteMaria Valeria CorriasAchille IolasconMario CapassoPublished in: BMC medical genetics (2019)
These findings may help to understand the molecular mechanisms by which low oxygen levels reshape gene signatures and provide new direction for hypoxia targeting in solid tumor.