Small-fibre damage is associated with distinct sensory phenotypes in patients with fibromyalgia and small-fibre neuropathy.
Caterina LeoneEleonora GalosiNicoletta EspositoPietro FalcoAlessandra FasolinoGiuseppe Di PietroGiulia Di StefanoFilippo CamerotaJan VollertAndrea TruiniPublished in: European journal of pain (London, England) (2022)
Our findings indicate that small-fibre damage is associated with distinct sensory phenotypes in patients with fibromyalgia and in patients with small-fibre neuropathy. The lack of phenotype differences between patients with fibromyalgia with and without small-fibre pathology and the relatively high frequency of the healthy phenotype in these patients highlight a complex relationship between small-fibre pathology and pain in patients with fibromyalgia.