Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells.
C WuPaul Y KimL L SwystunP C LiawJ I WeitzPublished in: Journal of thrombosis and haemostasis : JTH (2016)
PC and TAFI are concurrently activated in a TM-dependent manner and do not compete for the thrombin-TM complex, raising the possibility that they interact with distinct activation complexes. EPCR selectively enhances PC activation so that PC and TAFI activation kinetics become comparable on endothelial cells.