A new fluorescent and colorimetric chemosensor for Al 3+ and F - /CN - based on a julolidine unit and its bioimaging in living cells.
Fangfang LiuCongbin FanYayi TuShouzhi PuPublished in: RSC advances (2018)
A novel multifunctional chemosensor HL bearing a julolidine unit and a Schiff base unit has been synthesized. As a fluorescent sensor, HL exhibited excellent selectivity and high sensitivity to Al 3+ and F - /CN - with a low detection limit in acetonitrile. Moreover, HL also showed good colorimetric selectivity to F - /CN - ; a solution color change from colorless to light yellow in acetonitrile was observed by the 'naked-eye'. The properties of HL with Al 3+ and F - /CN - were studied by UV-vis absorption spectroscopy, fluorescence spectroscopy, high-resolution mass spectrometry and 1 H NMR titration. Furthermore, the cell imaging experimental results indicated that the chemosensor HL could be applied for the detection of Al 3+ in living cells.
Keyphrases
- living cells
- single molecule
- fluorescent probe
- high resolution
- lymph node metastasis
- high resolution mass spectrometry
- solid state
- aqueous solution
- liquid chromatography
- label free
- magnetic resonance
- drug delivery
- mass spectrometry
- real time pcr
- nitric oxide
- cancer therapy
- quantum dots
- bone marrow
- fluorescence imaging