The role of the tumour microenvironment in the angiogenesis of pituitary tumours.

Pedro MarquesSayka BarryEivind CarlsenDavid CollierAmy RonaldsonNeil DorwardJoan GrieveNigel MendozaRamesh NairSamiul MuquitAshley B GrossmanMarta Korbonits

Published in: Endocrine (2020)

M2 macrophages appear to play a role in PitNET neovascularisation, while B, CD4+ and FOXP3+ lymphocytes, as well as non-cellular TME elements such as CCL2, CXCL10 and CX3CL1, may also modulate the angiogenesis of PitNETs.

Keyphrases

endothelial cells
vascular endothelial growth factor
regulatory t cells
stem cells
wound healing
peripheral blood
liver injury
liver fibrosis
growth hormone
nk cells