Impact of sidedness of colorectal cancer on tumor immunity.

Chie TakasuMasaaki NishiKozo YoshikawaTakuya TokunagaHideya KashiharaToshiaki YoshimotoMitsuo Shimada

Published in: PloS one (2020)

The prognostic factors were IDO in right-sided CRC and PD-L1 and Foxp3 in left-sided CRC. These findings indicated that tumor immunity might play different roles depending upon sidedness. Tumor location may be an important factor to consider when assessing immune response and therapeutic decisions in CRC patients.

Keyphrases

prognostic factors
immune response
end stage renal disease
newly diagnosed
ejection fraction
regulatory t cells
peritoneal dialysis
inflammatory response
patient reported outcomes