HTLV-1 proviral load in infective dermatitis associated with HTLV-1 does not increase after the development of HTLV-1-associated myelopathy/tropical spastic paraparesis and does not decrease after IDH remission.
Everton S BatistaPedro D OliveiraJaneusa PrimoCinthya Maria Neves VarandasAna Paula NunesAchiléa Lisboa BittencourtLourdes FarrePublished in: PLoS neglected tropical diseases (2019)
High PVL in IDH patients was not necessary indicative of progression to HAM/TSP. PVL did not decrease after IDH remission. The maintenance of high PVL after remission could favor early development of ATL. Therefore, IDH patients would have to be followed-up even after remission of IDH and for a long period of time.