Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.
Julie HahnYi-Ping FuMichael R BrownJoshua C BisPaul S de VriesMary F FeitosaLisa R YanekStefan WeissFranco GiulianiniAlbert Vernon SmithXiuqing GuoTraci M BartzDiane M BeckerLewis C BeckerEric BoerwinkleJennifer A BrodyYii-Der Ida ChenOscar H FrancoMegan GroveTamara B HarrisAlbert HofmanShih-Jen HwangBrian G KralLenore J LaunerMarcello R P MarkusKenneth M RiceStephen S RichPaul M RidkerFernando RivadeneiraJerome I RotterNona SotoodehniaKent D TaylorAndré G UitterlindenUwe VölkerHenry VölzkeJie YaoDaniel I ChasmanMarcus DörrVilmundur G GudnasonRasika A MathiasWendy PostBruce M PsatyAbbas DehghanChristopher J O'DonnellAlanna C MorrisonPublished in: PloS one (2020)
This study identified one known locus (ANGPTL4) and four new loci (PLCL1, RC3H2, TMPRSS5, and LDLRAD1) associated with cardiovascular disease risk that warrant further investigation.