Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.

James A ReihillBrian WalkerRobert A HamiltonTimothy E G FergusonJ Stuart ElbornM Jackson StuttsBrian J HarveyVinciane Saint-CriqSiobhan M HendrickS Lorraine Martin

Published in: American journal of respiratory and critical care medicine (2017)

QUB-TL1 corrects aberrant CAP activities, providing a mechanism to delay or prevent the development of CF lung disease in a manner independent of CF transmembrane conductance regulator mutation.

Keyphrases

cystic fibrosis
pseudomonas aeruginosa
lung function
transcription factor