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Who's slipping through the cracks? A comprehensive individual, clinical and health system characterization of people with virological failure on first-line HIV treatment in Uganda and South Africa.

Zahra ReynoldsSuzanne M McCluskeyMahomed Yunus S MoosaRebecca F GilbertSelvan PillayIsaac AturindaKevin L ArdWinnie MuyindikeNicholas MusinguziGodfrey MasettePravi MoodleyJaysingh BrijkumarTamlyn RautenbergGavin GeorgeBrent A JohnsonRajesh T GandhiHenry SunpathVincent C MarconiMwebesa Bosco BwanaMark J Siedner
Published in: HIV medicine (2021)
Patients failing first-line ART in sub-Saharan Africa generally report high rates of adherence to ART, have extremely high rates of HIV drug resistance and utilize significant health care resources. Health systems interventions to promptly detect and manage treatment failure will be a prerequisite to establishing control of the HIV epidemic.
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