Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity.
Jessica M V PinoVitória F SilvaMarcos Mônico-NetoDanielle C SevaMelissa Y KatoJuly N AlvesGabriela Cruz PereiraHanna Karen M AntunesThales D GalvaoLia R A BitterncourtSergio TufikLysien I ZambranoAna R DâmasoLila M OyamaDavid ThivelRaquel Munhoz da Silveira CamposKil Sun LeePublished in: International journal of endocrinology (2023)
Iron is an essential micronutrient for several metabolic pathways. Thus, iron dyshomeostasis observed in severe obesity may aggravate the cognitive impairment by altering metabolic homeostasis and enhancing oxidative stress. These findings can contribute to searching for biomarkers that indicate cognitive performance in the population with obesity.