Vitamin B12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions.

Pauline MoscaAurélie RobertJean-Marc AlbertoMarie MeyerUrbi KunduSebastien HergalantRémy UmoretDavid CoelhoJean-Louis GuéantBruno LeheupNatacha Dreumont

Published in: Molecular nutrition & food research (2021)

Our data show that m6A methylation in mRNA could be one of the contributing mechanisms that underlie the neurological manifestations produced by vitamin B12 deficiency.

Keyphrases

genome wide
dna methylation
binding protein
replacement therapy
electronic health record
cerebral ischemia
big data
machine learning
blood brain barrier
data analysis
artificial intelligence