Proteomic analysis of the esophageal epithelium reveals key features of eosinophilic esophagitis pathophysiology.
Francisca Molina-JiménezLola Ugalde-TriviñoLaura Arias-GonzálezCarlos Relaño-RupérezSergio Casabona FrancésMaría Teresa Pérez-FernándezVerónica Martín DomínguezJennifer Fernández-PachecoEmilio José Laserna-MendietaPatricia Muñoz-HernándezÁngel AriasAinara CanoJavier MunozAlfredo J LucendoCecilio Santander VaqueroPedro MajanoPublished in: Allergy (2023)
We unraveled for the first time key proteomic features involved in EoE pathogenesis. An integrative analysis of transcriptomic and proteomic datasets provides a deeper insight than transcriptomic alone into understanding complex disease mechanisms.