A comparison of human serum and plasma metabolites using untargeted 1H NMR spectroscopy and UPLC-MS.

Manuja KaluarachchiClaire L BoulangéIbrahim KaramanJohn C LindonTimothy M D EbbelsPaul ElliottRussell P TracyNels C Olson

Published in: Metabolomics : Official journal of the Metabolomic Society (2018)

Correction for inter-individual variation was required to detect metabolite differences between serum and plasma. Our results suggest the potential importance of inter-individual effects and sample type on the results from serum and plasma metabolic phenotyping studies.

Keyphrases

mass spectrometry
ms ms
multiple sclerosis
high throughput
climate change
liquid chromatography
high resolution
gas chromatography