Metformin-induced changes in the gut microbiome and plasma metabolome are associated with cognition in men.
Marisel Rosell-DíazAnna Petit-GayClàudia Molas-PratLaura Gallardo-NuellLluís Ramió-TorrentàJosep Garre-OlmoVicente Pérez-BrocalAndrés MoyaMariona JovéReinald PamplonaJosep PuigRafael RamosFredrik BäckhedJordi Mayneris-PerxachsJosé Manuel Fernández-RealPublished in: Metabolism: clinical and experimental (2024)
The beneficial effects of metformin may be mediated by changes in the composition of the gut microbiota and microbial-host-derived co-metabolites.