Vancomycin-associated nephrotoxicity in non-critically ill patients admitted in a Brazilian public hospital: A prospective cohort study.

Claudmeire Dias Carneiro de AlmeidaAna Cristina Dos Santos LopesJoão Antonio de Queiroz OliveiraIsabela Soares Fonseca BatistaFernando Henrique PereiraJosé Eduardo GonçalvesVandack NobreMaria Auxiliadora Parreiras Martins

Published in: PloS one (2019)

Our study showed that usual doses of vancomycin did not reach recommended therapeutic serum trough levels of vancomycin in non-critically ill patients. Besides that, nephrotoxicity was common in this population, being associated with male sex, concomitant use of piperacillin-tazobactam and supra-therapeutic trough serum levels of vancomycin.

Keyphrases

methicillin resistant staphylococcus aureus
healthcare
staphylococcus aureus
mental health
drug induced
gram negative
multidrug resistant