Carcinoembryonic antigen-targeted photodynamic therapy in colorectal cancer models.

Fortuné M K ElekonawoDesirée L BosDavid M GoldenbergOtto C BoermanMark Rijpkema

Published in: EJNMMI research (2019)

Our findings suggest cells (and tumors) have different levels of susceptibility for tPDT even though they all express CEA. Furthermore, tPDT can effectively reduce tumor growth in vivo.

Keyphrases

photodynamic therapy
induced apoptosis
cell cycle arrest
cancer therapy
fluorescence imaging
oxidative stress
cell death