Quercetin declines LPS induced inflammation and augments adiponectin expression in 3T3-L1 differentiated adipocytes SIRT-1 dependently.

Zahra NooriMohammad Sharifi Sanaz Dastghaib Fatemeh Basiri Kejani Fatemeh RoohyZahra AnsariMohammad Hassan Maleki Morvarid Siri Sayed Mohammad Shafiee

Published in: Molecular biology reports (2024)

This study revealed that QCT treatment reduced crucial pro-inflammatory cytokines levels and increased adiponectin levels following LPS treatment. This finding implies that SIRT-1 may be a crucial factor for the anti-inflammatory activity of QCT.

Keyphrases

lps induced
inflammatory response
oxidative stress
metabolic syndrome
insulin resistance
anti inflammatory
combination therapy