Molecular characterization of metastatic penile squamous cell carcinoma in developing countries and its impact on clinical outcomes: LACOG 2018 translational study.
Fernando Sabino Marques MonteiroAntonio Machado Alencar JuniorKarine Martins da TrindadeTaiane Francieli RebelattoFernando C MalufAntonia A GazzolaPablo M BarriosJoaquim BellmuntRafaela Gomes de JesusGyl Eanes Barros SilvaAntonio Augusto Lima Teixeira JuniorPhilippe E SpiessAndre P FayPublished in: The oncologist (2024)
This study demonstrated that molecular alterations in mPSCC from developing countries are similar to those from developed countries. Predictive biomarkers for immunotherapy response such as TMB high or MSI were not identified. Specific gene mutations may identify patients with worse prognoses and open new avenues for therapeutic development.