Targeting enhanced cell death represents a potential therapeutic strategy for VEXAS syndrome.
Soichiro AdachiYohei KirinoKana HigashitaniLisa HiraharaAyaka MaedaNobuyuki HoritaKaoru Takase-MinegishiRyusuke YoshimiHideaki NakajimaPublished in: Rheumatology advances in practice (2024)
This study confirms increased cell death of monocytes and neutrophils and damage-associated molecular patterns in VEXAS syndrome, and these findings may be valuable for drug screening, therapeutic strategies and as biomarkers.