Cannabidiol modulates hippocampal genes involved in mitochondrial function, ribosome biogenesis, synapse organization, and chromatin modifications.
João P D MachadoValéria de AlmeidaAntonio W ZuardiJaime E C HallakJosé A CrippaAndré Schwambach VieiraPublished in: Acta neuropsychiatrica (2024)
This dataset indicates a widespread decrease of electron transport chain and ribosome biogenesis transcripts in CA1, while chromatin modifications and synapse organization transcripts were increased following CBD administration for 7 days.