In vitro and in silico assessment of new beta amino ketones with antiplasmodial activity.
Gabriela Camila KrombauerKarla de Sena GuedesFelipe Fingir BanfiRenata Rachide NunesAmanda Luisa da FonsecaEzequias Pessoa de SiqueiraJéssica Côrrea Bezerra BelleiKézia Katiani Gorza ScopelFernando de Pilla VarottiBruno Antônio Marinho SanchezPublished in: Revista da Sociedade Brasileira de Medicina Tropical (2022)
The physicochemical properties of compound 1 were compatible with the set of criteria established by the Lipinski rule and demonstrated its potential as a drug prototype for antiplasmodial activity.