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Do patient characteristics affect EGFR tyrosine kinase inhibitor treatment outcomes? A network meta-analysis of real-world survival outcomes of East Asian patients with advanced non-small cell lung cancer treated with first-line EGFR-TKIs.

Huang-Chih ChangChin-Chou WangChia-Cheng TsengKuo-Tung HuangYu-Mu ChenYu-Ping ChangChien-Hao LaiWen-Feng FangMeng-Chih LinHung-Yi Chuang
Published in: Thoracic cancer (2023)
This NMA suggests that afatinib results in similar PFS to erlotinib and superior PFS than gefitinib in patients with Del19 mutant NSCLC, aged ≥65 years, with ECOG scores of 0-1, and with baseline brain metastasis.
Keyphrases
  • advanced non small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • small cell lung cancer
  • case report
  • white matter
  • resting state
  • multiple sclerosis
  • blood brain barrier
  • subarachnoid hemorrhage