Defining the molecular features of radiation-induced glioma: A systematic review and meta-analysis.

Jacqueline P WhitehouseMeegan HowlettAniello FedericoMarcel KoolRaelene EndersbyNicholas G Gottardo

Published in: Neuro-oncology advances (2021)

This comprehensive analysis highlights the major molecular features of RIGs, demonstrates their molecular distinction from many other astrocytomas and gliomas, and reveals potential genetic drivers and therapeutic targets for this currently fatal disease.

Keyphrases

radiation induced
radiation therapy
single molecule
high grade
genome wide
dna methylation
gene expression
copy number
climate change