Heterologous SARS-CoV-2 IgA neutralising antibody responses in convalescent plasma.
Samantha K DavisKevin John SelvaEster LopezEbene R HaycroftWen Shi LeeAdam K WheatleyJennifer J JunoAmy AdairPhillip PymmSamuel J RedmondNicholas A GherardinDale I GodfreyWai-Hong ThamStephen J KentAmy W ChungPublished in: Clinical & translational immunology (2022)
Overall, convalescent plasma IgA contributed to the neutralising antibody response of wild-type SARS-CoV-2 RBD and various RBD mutations. However, this response displayed large heterogeneity and was less potent than IgG.