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Diagnostic utility of DNA integrity number as an indicator of sufficient DNA quality in next-generation sequencing-based genomic profiling.

Kaho HiramatsuChiaki MatsudaKatsuhiro MasagoKazuhiro ToriyamaEiichi SasakiYasuko FujitaMasataka HanedaHiromichi EbiNoriko ShibataWaki Hosoda
Published in: American journal of clinical pathology (2023)
To predict successful NGS, the DNA quality of FFPE tissue can be easily and reliably assessed using the DIN and peak/base ratio.
Keyphrases
  • circulating tumor
  • cell free
  • single molecule
  • circulating tumor cells
  • copy number
  • nucleic acid
  • single cell
  • dna methylation