Impact of superimposed Clostridium difficile infection in Crohn's or ulcerative colitis flares in the outpatient setting.
Patrícia Guedes GarciaJúlio Maria Fonseca ChebliTarsila Campanha da Rocha RibeiroPedro Duarte GaburriFabio Heleno de Lima PaceKátia Valéria Bastos Dias BarbosaLívia Almeida CostaWilliam de Almeida CruzIsabelle Carvalho de AssisBernardo Rodriguez Mendes MoraesAlexandre ZaniniJulio Maria Fonseca ChebliPublished in: International journal of colorectal disease (2018)
In IBD outpatients presenting colitis flares, CDI is highly prevalent. Females, younger age, infliximab, and notably steroid therapy were independently associated with CDI. Most patients with CDI experienced mild-to-moderate disease, and prompt treatment with vancomycin was highly effective, which seems to reduce the serious complication risks.