Cardiac autonomic dysfunction in survivors of childhood acute lymphoblastic leukemia: The St. Jude Lifetime Cohort Study.

Lindsey ChristoffersenTodd M GibsonChing-Hong PuiVijaya JoshiRobyn E PartinDaniel M GreenJennifer Q LanctotCarrie R HowellDaniel A MulrooneyGregory T ArmstrongLeslie L RobisonMelissa M HudsonKristen K Ness

Published in: Pediatric blood & cancer (2020)

CAD was present in over one third of survivors and was associated with lower exercise capacity. Obese survivors and those exposed to cyclophosphamide with high doses of vincristine and/or corticosteroids were at greatest risk.

Keyphrases

acute lymphoblastic leukemia
young adults
coronary artery disease
type diabetes
metabolic syndrome
oxidative stress
high intensity
high dose
physical activity
heart failure
resistance training
obese patients
acute myeloid leukemia