Trend analysis of tuberculosis case notifications with scale-up of antiretroviral therapy and roll-out of isoniazid preventive therapy in Zimbabwe, 2000-2018.
Kudakwashe C TakarindaAnthony D HarriesTsitsi Mutasa-ApolloCharles SandyRegis C ChotoSimbarashe MabayaCephas MbitoCollins TimirePublished in: BMJ open (2020)
This study shows the population-level impact of the continued scale-up of ART among PLHIV and the national roll-out of IPT among those in ART care in reducing TB, particularly clinically diagnosed TB which is largely associated with HIV. There are further opportunities for continued mitigation of TB with increasing coverage of ART and in particular IPT which still has a low coverage.
Keyphrases
- antiretroviral therapy
- mycobacterium tuberculosis
- hiv infected
- hiv aids
- hiv positive
- human immunodeficiency virus
- hiv infected patients
- affordable care act
- quality improvement
- pulmonary tuberculosis
- healthcare
- palliative care
- climate change
- health insurance
- stem cells
- hiv testing
- emergency department
- pain management
- hepatitis c virus
- cell therapy
- bone marrow
- replacement therapy
- smoking cessation